Twyn from TheMittani.com has written an excellent article about using the Gnosis for PVP and exploration. It contains some good insight and a few staple sample fits. The gist is that the Gnosis has the base align time of a thrasher but not the velocity of an SFI or speed fit Talos. It contains bonuses to all conventional weapon systems in the game, including drones. The Gnosis has evenly spread resists, making it potentially a good active-tanked mission pick or a log-dependent wormhole ship. Its slot layout is 6/6/6 with good PG/CPU, meaning it can fit essentially anything and still put out, as long as you don’t fit it like this.
As far as flying the Gnosis in a PVP fleet goes, I have mixed feelings regarding its shininess. It’s not particularly shiny at the moment, running anywhere from 140-200M depending on region, yet we know that it will become shiny at some point in time, likely around 2015/2016 after the influx from the EVE First Decade Collector’s Edition BPCs has been consumed and more of the original stock has been killed off. I do think it’s an excellent solo boat though, thanks to its versatility and low align time. I do find it hard to recommend lasers however, even with the great projection offered by Scorch crystals in top-tier T2 guns. I just wish I had another one to play around with, or that I sunk my ISK into them when they were 120M in Jita. For the moment it seems mine will stay holed up in Jita, but maybe I’ll take it out and make some Gnosis PVP videos soon (or one short one, if I remember to press record at all).